Relationship between the severity of carpal tunnel syndrome and lipid profile in patients with tip 2 diabetes mellitus

Esra Aciman Demirel; Burcu Karpuz; Mustafa Açıkgöz; Hüsyin Tuğrul Atasoy

doi:10.28982/josam.843420

Araştırma Makalesi

Yıl 2021, Cilt: 5 Sayı: 1, 66 - 69, 01.01.2021

Esra Aciman Demirel Burcu Karpuz Mustafa Açıkgöz Hüsyin Tuğrul Atasoy

https://doi.org/10.28982/josam.843420

Öz

Kaynakça

1. Alanazy MH. Clinical and electrophysiological evaluation of carpal tunnel syndrome: approach and pitfalls. Neurosciences. 2017;22.3:169. doi: 10.17712/nsj.2017.3.20160638
2. Gelfman R, Melton LJ, Yawn BP, Wollan PC, Amadio PC, Stevens JC. Long-term trends in carpal tunnel syndrome. Neurology. 2009;72:33–41. doi: 10.1212/01.wnl.0000338533.88960.b9
3. de Krom MC, de Krom CJ, Spaans F. Carpal tunnel syndrome: diagnosis,treatment, prevention and its relevance to dentistry. Ned Tijdschr Tandheelkd. 2009;116:97-101.
4. Yalçın Ü. Vitamin D eksikliği ve karpal tünel sendromu arasındaki ilişkinin değerlendirilmesi. Ahi Evran Med J. 2019;3(3):98-103.
5. Aydemir ŞU, Tekeşin A, Yıldırım A. Karpal Tünel Sendromu-Metabolik Sendrom İlişkisi. Bakırköy Tıp Dergisi. 2019;15:250-8. doi: 10.4274/BTDMJB.galenos.2019.20181227115429
6. Gül Yurdakul F, Bodur H, Öztop Çakmak Ö, Ateş C, Sivas F, Eser F, et al. On the Severity of Carpal Tunnel Syndrome: Diabetes or Metabolic Syndrome. J Clin Neurol. 2015;11:234-40. doi: 10.3988/jcn.2015.11.3.234
7. Alp R, Sargın H, Bulut G, Sargın M, Boru ÜT, Yayla A. Tip 1 Diyabetlilerde Periferik Nöropati ve Semptomatik Karap Tünel Sendromu Sıklığı. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi. 2004;15(2):87-9.
8. Pençe HH, Aktaş HŞ. Diyabetik Nöropatisi Olan Kişilerde Monosit/HDL Kolesterol Oranı ile Kardiyovasküler Risk Arasındaki İlişki. Online Türk Sağlık Bilimleri Dergisi. 2019;4(4):526-38. doi: 10.26453/otjhs.620725
9. Nakamichi KI, Tachibana S.Hypercholesterolemia as a risk factor for idiopathic carpal tunnel syndrome. Muscle & Nerve. 2005;32(3):364-7. doi: 10.1002/mus.20363
10. Watson JC. Electrodiagnostic approach to carpal tunnel syndrome. Neurol Clin. 2012;30:457–78. doi: 10.1016/j.ncl.2011.12.001
11. Nawar S, Alotaibi S, Saad S and Alqahtani M. The Prevalence and Patterns of Carpal Tunnel Syndrome and Their Associated Risk Factors Among Diabetic Population In South-West of Kingdom of Saudi Arabia. The Egyptian Journal of Hospital Medicine. 2018;70(7):1152-8. doi: 10.12816/0044542
12. Ebrahimzadeh MH, Mashhadinejad H, Moradi, Kachooei AR. Carpal tunnel release in diabetic and nondiabetic patients. Arch Bone Jt Surg. 2013;1(1):23-7.
13. Paranthakan C, Govindarajan PK. A study on carpal tunnel syndrome among diabetes patients in tertiary care hospital. Int J Community Med Public Health. 2016;3:805-7. doi: 10.18203/2394-6040.ijcmph20160908
14. Oktayoglu P, Nas K, Kilinc F, Tasdemir N, Bozkurt M, Yildiz I. Assessment of the Presence of Carpal Tunnel Syndrome in Patients with Diabetes Mellitus, Hypothyroidism and Acromegaly. J Clin Diagn Res. 2015;9(6):14-8. doi: 10.7860/JCDR/2015/13149.6101
15. Rydberg M, Zimmerman M, Gottsäter A, Nilsson PM, Melander O, Dahlin LB. Diabetes mellitus as a risk factor for compression neuropathy: a longitudinal cohort study from southern Sweden. BMJ Open Diab Res Care. 2020;8:e001298. doi: 10.1136 /bmjdrc-2020-001298
16. Akulwar AS, Ghugare BW, Singh R, Kanchankar N, Joshi M, Ramavat M. Clinical and electrophysiological evaluation of carpal tunnel syndrome in diabetes mellitus to assess association of age, gender and duration of diabetes on median neuropathy at wrist. The Health Agenda. 2013;1(3):71-6.
17. Islam MR, Rahman T, Islam RN, Habib R, Rahman A, Bhowmik NB, et al. Frequency of Carpal Tunnel Syndrome in Patients Having Diabetes Mellitus with Neuropathy in a Tertiary Care Hospital of Bangladesh. BIRDEM Medical Journal. 2018;8(3):240-5. doi: 10.3329/birdem.v8i3.38131
18. Perkins BA, David O, Vera B. Carpal tunnel syndrome in patients with diabetic polyneuropathy. Diabetes Care. 2002;25(3):565-9. doi: 10.2337/diacare.25.3.565
19. Pasnoor M, Dimachkie MM, Kluding P, Barohn RJ. Diabetic neuropathy part 1: overview and symmetric phenotypes. Neurol Clin. 2013;31(2):425-5. doi: 10.1016/j.ncl.2013.02.004
20. Komurcu HF, Kilic S, Anlar O. Relationship of age, body mass index, wrist and waist circumference to carpal tunnel severity. Neurol Med Chir. 2014;54:395-400. doi: 10.2176/nmc.oa2013-0028
21. Mansoor S, Siddiqui M , Mateen F , Saadat S , Khan ZH , Zahid M, et al. Prevalence of Obesity in Carpal Tunnel Syndrome Patients: A Cross-Sectional Survey. Cureus. 2017;9(7):1519-23. doi: 10.7759/cureus.1519
22. Nageeb RS, Shehta N, Nageeb GS, Omran AA. Body mass index and vitamin D level in carpal tunnel syndrome patients. The Egyptian journal of neurology psychiatry and neurosurgery. 2018;54(1):14. doi: 10.1186/s41983-018-0009-z
23. Awad El Gharieb H, Abd El Aleem El Gendy A, Aleem E, Hamed Rashad M, Mohammad Al Bazza O. Serum lipid profile in middle aged female patients with carpal tunnel syndrome. Al-Azhar Medical Journal. 2020;49(1):219-28. doi: 10.12816/amj.2020.67552
24. Pourmemari MH, R Shiri. Diabetes as a risk factor for carpal tunnel syndrome: a systematic review and meta‐analysis. Diabetic Medicine. 2016;33(1):10-6. doi: 10.1111/dme.12855
25. Nazish S, Zafar A, Shahid R, Al Sulaiman A, Alabdali M, Aljaafari D, et al. Electrophysiologic severity of carpal tunnel syndrome in diabetic patients of the Saudi population. Neurosciences (Riyadh, Saudi Arabia). 2019;24(1):22-8. doi: 10.17712/nsj.2019.1.20180217
26. Önder B, Yalçın E, Selçuk B, Kurtaran A, Akyüz M. Carpal tunnel syndrome and metabolic syndrome co-occurrence. Rheumatology international. 2013;33(3):583-6. doi: 10.1007/s00296-012-2417-1
27. Söğüt E, Avcı E, Üstüner F, Arıkan E. Serum aterojenite indeksi olarak (TG/HDL-K) oranının değerlendirilmesi. Türk Klinik Biyokimya Derg. 2006;4:1-8.
28. Miric DJ, Kisic BM, Filipovic-Danic S, Grbic R, Dragojevic I, Miric MB,Puhalo-Sladoje D. Xanthine oxidase activity in type 2 diabetes mellitus patients with and without diabetic peripheral neuropathy. Journal of diabetes research. 2016;4370490. doi: 10.1155/2016/4370490

Relationship between the severity of carpal tunnel syndrome and lipid profile in patients with tip 2 diabetes mellitus

Yıl 2021, Cilt: 5 Sayı: 1, 66 - 69, 01.01.2021

Esra Aciman Demirel Burcu Karpuz Mustafa Açıkgöz Hüsyin Tuğrul Atasoy

https://doi.org/10.28982/josam.843420

Öz

Background/Aim: Diabetes mellitus (DM) accelerates the development of neuropathy, and carpal tunnel syndrome (CTS) is the most common form of entrapment neuropathy. The pathogenesis of diabetic neuropathy is multifactorial with its vascular and metabolic factors. In this study, we aimed to evaluate the relationship among the electrophysiological severity of CTS, lipid profile and serum atherogenic index in patients with Type 2 DM.
Methods: In this hospital-based retrospective cross-sectional study, we retrospectively evaluated 202 type 2 DM patients, who presented to the electrophysiology laboratory of Zonguldak Bulent Ecevit University Faculty of Medicine between 2016-2019 and investigated the relationship among the electrophysiological severity of CTS, lipid profile and serum atherogenic index of 131 patients diagnosed with CTS.
Results: The patients with CTS had significantly higher values of fasting blood glucose and HbA1c compared to those without CTS (P=0.010). In terms of the severity of CTS, the patients were divided into three groups as mild, moderate, severe. In terms of the lipid panel, the mean values of cholesterol, triglyceride, and HDL-C were similar among the groups (P=0.098, P=0.321, P=0.706), while LDL-C levels were higher in the severe CTS group. (P=0.024). There was a significant positive correlation between age (R=0.126 P=0.004), HbA1c (R=0.245, P=0.002) and CTS severity.
Conclusion: We identified a relationship between CTS severity and LDL-C. CTS should be considered in patients with DM and hyperlipidemia. Further larger-scale studies with control groups are recommended.

Anahtar Kelimeler

Carpal tunnel syndrome, Low-density lipoprotein, Cholesterol, Serum atherogenic index

Kaynakça

1. Alanazy MH. Clinical and electrophysiological evaluation of carpal tunnel syndrome: approach and pitfalls. Neurosciences. 2017;22.3:169. doi: 10.17712/nsj.2017.3.20160638
2. Gelfman R, Melton LJ, Yawn BP, Wollan PC, Amadio PC, Stevens JC. Long-term trends in carpal tunnel syndrome. Neurology. 2009;72:33–41. doi: 10.1212/01.wnl.0000338533.88960.b9
3. de Krom MC, de Krom CJ, Spaans F. Carpal tunnel syndrome: diagnosis,treatment, prevention and its relevance to dentistry. Ned Tijdschr Tandheelkd. 2009;116:97-101.
4. Yalçın Ü. Vitamin D eksikliği ve karpal tünel sendromu arasındaki ilişkinin değerlendirilmesi. Ahi Evran Med J. 2019;3(3):98-103.
5. Aydemir ŞU, Tekeşin A, Yıldırım A. Karpal Tünel Sendromu-Metabolik Sendrom İlişkisi. Bakırköy Tıp Dergisi. 2019;15:250-8. doi: 10.4274/BTDMJB.galenos.2019.20181227115429
6. Gül Yurdakul F, Bodur H, Öztop Çakmak Ö, Ateş C, Sivas F, Eser F, et al. On the Severity of Carpal Tunnel Syndrome: Diabetes or Metabolic Syndrome. J Clin Neurol. 2015;11:234-40. doi: 10.3988/jcn.2015.11.3.234
7. Alp R, Sargın H, Bulut G, Sargın M, Boru ÜT, Yayla A. Tip 1 Diyabetlilerde Periferik Nöropati ve Semptomatik Karap Tünel Sendromu Sıklığı. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi. 2004;15(2):87-9.
8. Pençe HH, Aktaş HŞ. Diyabetik Nöropatisi Olan Kişilerde Monosit/HDL Kolesterol Oranı ile Kardiyovasküler Risk Arasındaki İlişki. Online Türk Sağlık Bilimleri Dergisi. 2019;4(4):526-38. doi: 10.26453/otjhs.620725
9. Nakamichi KI, Tachibana S.Hypercholesterolemia as a risk factor for idiopathic carpal tunnel syndrome. Muscle & Nerve. 2005;32(3):364-7. doi: 10.1002/mus.20363
10. Watson JC. Electrodiagnostic approach to carpal tunnel syndrome. Neurol Clin. 2012;30:457–78. doi: 10.1016/j.ncl.2011.12.001
11. Nawar S, Alotaibi S, Saad S and Alqahtani M. The Prevalence and Patterns of Carpal Tunnel Syndrome and Their Associated Risk Factors Among Diabetic Population In South-West of Kingdom of Saudi Arabia. The Egyptian Journal of Hospital Medicine. 2018;70(7):1152-8. doi: 10.12816/0044542
12. Ebrahimzadeh MH, Mashhadinejad H, Moradi, Kachooei AR. Carpal tunnel release in diabetic and nondiabetic patients. Arch Bone Jt Surg. 2013;1(1):23-7.
13. Paranthakan C, Govindarajan PK. A study on carpal tunnel syndrome among diabetes patients in tertiary care hospital. Int J Community Med Public Health. 2016;3:805-7. doi: 10.18203/2394-6040.ijcmph20160908
14. Oktayoglu P, Nas K, Kilinc F, Tasdemir N, Bozkurt M, Yildiz I. Assessment of the Presence of Carpal Tunnel Syndrome in Patients with Diabetes Mellitus, Hypothyroidism and Acromegaly. J Clin Diagn Res. 2015;9(6):14-8. doi: 10.7860/JCDR/2015/13149.6101
15. Rydberg M, Zimmerman M, Gottsäter A, Nilsson PM, Melander O, Dahlin LB. Diabetes mellitus as a risk factor for compression neuropathy: a longitudinal cohort study from southern Sweden. BMJ Open Diab Res Care. 2020;8:e001298. doi: 10.1136 /bmjdrc-2020-001298
16. Akulwar AS, Ghugare BW, Singh R, Kanchankar N, Joshi M, Ramavat M. Clinical and electrophysiological evaluation of carpal tunnel syndrome in diabetes mellitus to assess association of age, gender and duration of diabetes on median neuropathy at wrist. The Health Agenda. 2013;1(3):71-6.
17. Islam MR, Rahman T, Islam RN, Habib R, Rahman A, Bhowmik NB, et al. Frequency of Carpal Tunnel Syndrome in Patients Having Diabetes Mellitus with Neuropathy in a Tertiary Care Hospital of Bangladesh. BIRDEM Medical Journal. 2018;8(3):240-5. doi: 10.3329/birdem.v8i3.38131
18. Perkins BA, David O, Vera B. Carpal tunnel syndrome in patients with diabetic polyneuropathy. Diabetes Care. 2002;25(3):565-9. doi: 10.2337/diacare.25.3.565
19. Pasnoor M, Dimachkie MM, Kluding P, Barohn RJ. Diabetic neuropathy part 1: overview and symmetric phenotypes. Neurol Clin. 2013;31(2):425-5. doi: 10.1016/j.ncl.2013.02.004
20. Komurcu HF, Kilic S, Anlar O. Relationship of age, body mass index, wrist and waist circumference to carpal tunnel severity. Neurol Med Chir. 2014;54:395-400. doi: 10.2176/nmc.oa2013-0028
21. Mansoor S, Siddiqui M , Mateen F , Saadat S , Khan ZH , Zahid M, et al. Prevalence of Obesity in Carpal Tunnel Syndrome Patients: A Cross-Sectional Survey. Cureus. 2017;9(7):1519-23. doi: 10.7759/cureus.1519
22. Nageeb RS, Shehta N, Nageeb GS, Omran AA. Body mass index and vitamin D level in carpal tunnel syndrome patients. The Egyptian journal of neurology psychiatry and neurosurgery. 2018;54(1):14. doi: 10.1186/s41983-018-0009-z
23. Awad El Gharieb H, Abd El Aleem El Gendy A, Aleem E, Hamed Rashad M, Mohammad Al Bazza O. Serum lipid profile in middle aged female patients with carpal tunnel syndrome. Al-Azhar Medical Journal. 2020;49(1):219-28. doi: 10.12816/amj.2020.67552
24. Pourmemari MH, R Shiri. Diabetes as a risk factor for carpal tunnel syndrome: a systematic review and meta‐analysis. Diabetic Medicine. 2016;33(1):10-6. doi: 10.1111/dme.12855
25. Nazish S, Zafar A, Shahid R, Al Sulaiman A, Alabdali M, Aljaafari D, et al. Electrophysiologic severity of carpal tunnel syndrome in diabetic patients of the Saudi population. Neurosciences (Riyadh, Saudi Arabia). 2019;24(1):22-8. doi: 10.17712/nsj.2019.1.20180217
26. Önder B, Yalçın E, Selçuk B, Kurtaran A, Akyüz M. Carpal tunnel syndrome and metabolic syndrome co-occurrence. Rheumatology international. 2013;33(3):583-6. doi: 10.1007/s00296-012-2417-1
27. Söğüt E, Avcı E, Üstüner F, Arıkan E. Serum aterojenite indeksi olarak (TG/HDL-K) oranının değerlendirilmesi. Türk Klinik Biyokimya Derg. 2006;4:1-8.
28. Miric DJ, Kisic BM, Filipovic-Danic S, Grbic R, Dragojevic I, Miric MB,Puhalo-Sladoje D. Xanthine oxidase activity in type 2 diabetes mellitus patients with and without diabetic peripheral neuropathy. Journal of diabetes research. 2016;4370490. doi: 10.1155/2016/4370490

Toplam 28 adet kaynakça vardır.

Ayrıntılar

Birincil Dil	İngilizce
Konular	Sinirbilim
Bölüm	Araştırma makalesi
Yazarlar	Esra Aciman Demirel 0000-0002-1444-5022 Burcu Karpuz 0000-0003-3171-1123 Mustafa Açıkgöz 0000-0002-0645-5765 Hüsyin Tuğrul Atasoy 0000-0003-1631-7400
Yayımlanma Tarihi	1 Ocak 2021
Yayımlandığı Sayı	Yıl 2021 Cilt: 5 Sayı: 1

Kaynak Göster

APA	Aciman Demirel, E., Karpuz, B., Açıkgöz, M., Atasoy, H. T. (2021). Relationship between the severity of carpal tunnel syndrome and lipid profile in patients with tip 2 diabetes mellitus. Journal of Surgery and Medicine, 5(1), 66-69. https://doi.org/10.28982/josam.843420
AMA	Aciman Demirel E, Karpuz B, Açıkgöz M, Atasoy HT. Relationship between the severity of carpal tunnel syndrome and lipid profile in patients with tip 2 diabetes mellitus. J Surg Med. Ocak 2021;5(1):66-69. doi:10.28982/josam.843420
Chicago	Aciman Demirel, Esra, Burcu Karpuz, Mustafa Açıkgöz, ve Hüsyin Tuğrul Atasoy. “Relationship Between the Severity of Carpal Tunnel Syndrome and Lipid Profile in Patients With Tip 2 Diabetes Mellitus”. Journal of Surgery and Medicine 5, sy. 1 (Ocak 2021): 66-69. https://doi.org/10.28982/josam.843420.
EndNote	Aciman Demirel E, Karpuz B, Açıkgöz M, Atasoy HT (01 Ocak 2021) Relationship between the severity of carpal tunnel syndrome and lipid profile in patients with tip 2 diabetes mellitus. Journal of Surgery and Medicine 5 1 66–69.
IEEE	E. Aciman Demirel, B. Karpuz, M. Açıkgöz, ve H. T. Atasoy, “Relationship between the severity of carpal tunnel syndrome and lipid profile in patients with tip 2 diabetes mellitus”, J Surg Med, c. 5, sy. 1, ss. 66–69, 2021, doi: 10.28982/josam.843420.
ISNAD	Aciman Demirel, Esra vd. “Relationship Between the Severity of Carpal Tunnel Syndrome and Lipid Profile in Patients With Tip 2 Diabetes Mellitus”. Journal of Surgery and Medicine 5/1 (Ocak 2021), 66-69. https://doi.org/10.28982/josam.843420.
JAMA	Aciman Demirel E, Karpuz B, Açıkgöz M, Atasoy HT. Relationship between the severity of carpal tunnel syndrome and lipid profile in patients with tip 2 diabetes mellitus. J Surg Med. 2021;5:66–69.
MLA	Aciman Demirel, Esra vd. “Relationship Between the Severity of Carpal Tunnel Syndrome and Lipid Profile in Patients With Tip 2 Diabetes Mellitus”. Journal of Surgery and Medicine, c. 5, sy. 1, 2021, ss. 66-69, doi:10.28982/josam.843420.
Vancouver	Aciman Demirel E, Karpuz B, Açıkgöz M, Atasoy HT. Relationship between the severity of carpal tunnel syndrome and lipid profile in patients with tip 2 diabetes mellitus. J Surg Med. 2021;5(1):66-9.

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