Öz
Isolated renal glucosuria is defined as urinary excretion of glucose when the blood glucose level is normal. It is a rare and benign disease. The majority of the cases are asymptomatic. Most cases of isolated glycosuria, which are diagnosed by complete urinalysis and exclusion of other diseases that cause glycosuria, are followed up without treatment. Diabetes mellitus must be excluded before the diagnosis of isolated renal glucosuria. In this article, we presented a case who did not have any symptoms and underwent diagnostic evaluation due to glycosuria.
Anahtar Kelimeler
Kaynakça
- Scholl-Bürgi S, Santer R, Ehrich JH. Long-term outcome of renal glucosuria type 0: the original patient and his natural history. Nephrol Dial Transplant. 2004;19:2394-6.
- Calado J, Loeffler J, Sakallioglu O, et al. Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting. Kidney Int. 2006;69:852-5.
- Magen D, Sprecher E, Zelikovic I, et al. A novel missense mutation in SLC5A2 encoding SGLT2 underlies autosomal-recessive renal glucosuria and aminoaciduria. Kidney Int. 2005;67:34- 41.
- Francis J, Zhang J, Farhi A, et al. A novel SGLT2 mutation in a patient with autosomal recessive renal glucosuria. Nephrol Dial Transplant. 2004;19:2893-5.
- Calado J, Soto K, Clemente C, Correia P, Rueff J. Novel compound heterozygous mutations in SLC5A2 are responsible for autosomal recessive renal glucosuria. Hum Genet. 2004;114:314- 6.
- Dönmez O, Köse H. Çocuklarda Renal glukozüri. Güncel Pediatri. 2004;2:134-6.
- Wu CJ. Transient renal glycosuria in a patient with acute pyelonephritis. Intern Med. 2001;40:519-21.
- Sodeman, W.A, Sodeman, T.M.: Sodeman’s Pathologic Physiology, Mechanisms of disease, W.B, Saunders Co., Philadelphia, 6 th Ed. 1979;415:87.
Öz
İzole renal glukozüri, kan glukoz seviyesinin normal olduğu durumlarda glukozun idrar yoluyla atılması olarak tanımlanmaktadır. Nadir ve benign karakterli bir hastalıktır. Olguların çoğu semptom vermemektedir. Tam idrar tetkik sonucu ve diğer glukozüri yapan hastalıkların dışlanması ile teşhis alan izole glukozüri olguların çoğu tedavi edilmeksizin takibe alınmaktadır. İzole renal glukozüri tanısı öncesi mutlaka diyabetes mellitus dışlanması şarttır. Bu yazımızda herhangi bir semptomu olmayan ve glukozüri nedeniyle tanısal değerlendirilmesi yapılan olguyu sunuyoruz.
Anahtar Kelimeler
Kaynakça
- Scholl-Bürgi S, Santer R, Ehrich JH. Long-term outcome of renal glucosuria type 0: the original patient and his natural history. Nephrol Dial Transplant. 2004;19:2394-6.
- Calado J, Loeffler J, Sakallioglu O, et al. Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting. Kidney Int. 2006;69:852-5.
- Magen D, Sprecher E, Zelikovic I, et al. A novel missense mutation in SLC5A2 encoding SGLT2 underlies autosomal-recessive renal glucosuria and aminoaciduria. Kidney Int. 2005;67:34- 41.
- Francis J, Zhang J, Farhi A, et al. A novel SGLT2 mutation in a patient with autosomal recessive renal glucosuria. Nephrol Dial Transplant. 2004;19:2893-5.
- Calado J, Soto K, Clemente C, Correia P, Rueff J. Novel compound heterozygous mutations in SLC5A2 are responsible for autosomal recessive renal glucosuria. Hum Genet. 2004;114:314- 6.
- Dönmez O, Köse H. Çocuklarda Renal glukozüri. Güncel Pediatri. 2004;2:134-6.
- Wu CJ. Transient renal glycosuria in a patient with acute pyelonephritis. Intern Med. 2001;40:519-21.
- Sodeman, W.A, Sodeman, T.M.: Sodeman’s Pathologic Physiology, Mechanisms of disease, W.B, Saunders Co., Philadelphia, 6 th Ed. 1979;415:87.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | İç Hastalıkları |
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 31 Ekim 2023 |
| Gönderilme Tarihi | 22 Ağustos 2023 |
| Yayımlandığı Sayı | Yıl 2023 Cilt: 1 Sayı: 3 |
